Flatness of the Meckel cave may cause primary trigeminal neuralgia: a radiomics-based study

Abstract Background Neurovascular contact (NVC) is the main cause of primary trigeminal neuralgia (PTN); however, cases PTN without NVC are still observed. In this study, Meckel cave (MC) morphology in were analyzed by radiomics and compared to healthy controls (HCs) explore PTN. Methods We studied 3.0T MRI data 115 patients with 46 HCs. Bilateral MC was modeled using 3D Slicer software, morphological characteristics method. Results The right side incidence rate group higher than left incidence. By analyzing flatness feature MC, we observed that affected lower unaffected side, HC bilateral side. Conclusions providing a method analyze found there an asymmetry groups. It can be inferred may